Urinary System:Early Filtrate Processing 1. What are the two reabsorption pathwa
ID: 3480476 • Letter: U
Question
Urinary System:Early Filtrate Processing 1. What are the two reabsorption pathways through the tubular cell barrier? 2. 2. How can we cause water to diffuse from the lumen into the interstitial space? 3. Transport of what ion could cause the diffusion in question 2? 4. Summarize reabsorption in the proximal tubule 5. What percent of the filtrate is reabsorbed in the proximal tubule? 6. The simple squamous cells of the thin descending loop are permeable to but impermeable to 7. The ascending limb of the loop of Henle is permeable to but impermeable to 8. What is the role of the loop of Henle? 9. What is the role of the vasa recta? 10. From the Quiz section, what does furosemide do?Explanation / Answer
1] 1. transcellular ( through luminal or basolateral membrane)
2. paracellular ( through tight junctions)
2} The driving force for water reabsorption is the transcellular osmotic gradient.
3] Transport of Na+ causes diffusion of water from lumen into the interstitium.
4] In proximal tubule reabsorption of water, Na+, Cl-, K+, HCO3- and almost all the filtered glucose and aminoacids.
5] 67% of filtrate is reabsorbed in proximal tubule.
6] Thin descending loop of henle is permeable to water but impermeable to urea and ions.
7] Thick ascending limb is permeable to ions but impermeable to water.
8] Loop of henle, that conducts urine within each nephron. This function allows production of urine that is, far more concentrated than blood, lmiting the amount of water needed as intake for survival.
9] Vasa recta helps in counter current exchange. Regulation of blood is important for maintaining counter current exchange between vasa recta and loop of henle, these two components work together to process and filter blood to remove impurities before sending it else where in the urinary system and through out the body.
10] Furosemide is a potent diuretic that is used to eliminate water and salt from the body.
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