Uriaary System: Late Filtrate Processing L. Name the types two types of cells in

Question

Uriaary System: Late Filtrate Processing L. Name the types two types of cells in the cortical collecting ducts and describe their function 2. a. Aldosterone is stimulated by an increase or decrease in what ions? What does aldosterone increase in the basolateral membrane? What does antidiuretic hormone (ADH) increase in the fuminal membrane? 4 In dehydration and overhydration, what would be the levels of dehydration-_ overhydeation ( or ) a ADH7 b. Aldosterone __dehydration overhydration ( or ) 5. Describe what moveis) out of the tubule and what the osmolarity would be in the following nephron segments a Proximal tubule b. Descending limb c. Ascending limb d. Late distal tubule moveys) out , move(s)out moves out mOsm movels yout mOsm By the medullary collecting dugt, only b. Under the following conditions, report the levels of ADH and subsequent urine osmolarity and to 6. %ofthe fillne muins & ADH Urine Osmolarity Urine Volume Hydration Normal Dehydration Overhydration

Explanation / Answer

1] 1. Principal cells

Functions: They are involved in sodium reabsorption and ADH-induced water reabsorption.

2. Intercalated cells

Functions: They are involved in acid secretion and bicarbonate transport.

2] 1. Aldosterone is stimulated by increase in K+ ions.

2. And it is stimulated by decrease in Na+ ions.

3] Increased plasma osmolality, decreased ECF volume, decreased blood pressure, angiotensin 2 causes increase in ADH in luminal membrane.

4] a. ADH levels: it increses in dehydration and its level decreases in overhydration.

b. Aldosterone levels: its level increases in dehydration and decreases in overhydration.

5] a. Proximal tubule: water moves out. osmolality is about 285mosm/L

b. Descending limb: water moves out and the osmolality is about 1400mosm/kg

c. Ascending limb: Na+ and Cl- moves out and the osmolality is about 100mosm/L

d. Late distal tubule: Na+ moves out and the osmolality is about 100mosm/L

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