Pre-Lab Exercise 25-3 Glomerular Filtration and Tubular Reabsorption Table 25, I

ID: 3483544 • Letter: P

Question

Pre-Lab Exercise 25-3 Glomerular Filtration and Tubular Reabsorption Table 25, I lists chemicals textbook for reference and cells found in blood. Do the following for each chemical, using your cut istd sabseane fiered at the plomerulus (in, if i is able to leave the blood and enter the nephron to become part of the filerane) 2 If the substance is found falerate, in the Eltrate, determine if the substance is reabuorhed into the blood or if it is found in the urine. 3 If the sabstance is reabsorbed into the blood, determine where this sebstance is AE25.1 Substances F Substance Erythrocyte ound in the Blood and Their Filtration and Reabsorption by the Nephron Filtered in the Clomerulus? Reabsorbed? Location Where Reabsorption Takes Place Leukocyte Water Glucose Proteins Amino acids Urea Creatinine 25 Electrolytes (sodium, potassium, chloride) Uric acid Ketones 614 I Exploring Anatomy&Physiology; in the Laboratory

Explanation / Answer

Substance

Filtered in the glomerulus (Yes/No)

Reabsorbed (Yes/No)

Location where reabsorption takes place

Erythrocyte

Reabsorption of erythrocytes does not occur.

Leukocyte

Reabsorption of leukocyte does not occur.

Water

Yes

Water is majorly reabsorbed in the proximal convoluted tubule. Water is also reabsorbed in the loop of Henle. More or less water, depending upon body needs, is also reabsorbed in the distal convoluted tubule.

Glucose

Yes

The SGLT2 cotransporter in the proximal tubule co-transports glucose with sodium ions into the walls of the proximal convoluted tubule. Glucose enters into the blood capillaries from the walls of the proximal convoluted tubule along concentration gradient.

Proteins

Yes

Reabsorption of proteins takes place in the proximal convoluted tubule.

Amino acids

Yes

Reabsorption of amino acids takes place in the proximal convoluted tubule.

Urea

Yes

Approximately 60% of filtered urea is reabsorbed

50% of the filtered urea is reabsorbed in the proximal convoluted tubule. Some amount of urea is also reabsorbed in the medullary collecting ducts.

Creatinine

Yes

Creatinine is not reabsorbed but it is excreted out.

Electrolytes (Sodium, Potassium, Chloride)

Yes

Electrolytes are reabsorbed in the proximal convoluted tubule and the descending loop of Henle.

Uric acid

Yes

Urea is reabsorbed in the proximal convoluted tubule.

Ketones

Reabsorption of ketones does not occur.