Before After ft Plot x trol thed EPP size (m) EPP size (mv) mEPP size (mV) latey

Question

Before After ft Plot x trol thed EPP size (m) EPP size (mv) mEPP size (mV) latey the smEPPsize (mV) Question 7: What does the left-most column in plot x indicate? (see arrow in plot x above) The number of times more than one synaptic vesicle was released when the presynaptic nerve was stimulated no vesicle was released, even though the presynaptic nerve was stimulated The number of times a single vesicle was released when the The number of times the muscle cell depolarized presynaptic nerve was stimulated when the presynaptic nerve was stimulated Which quantal analysis term is used to indicate what is counted in order to get the values in that left most column in plot x (see arrow in plot x above)? b. Vesicles d. Failures Question 9: The data for questions 7-10 were recorded from a musdle cell at one neuromuscular junction before Units (left) and after (right) an experimental manipulation that changed the strength of this synapse. Based on what we discussed in class, which ofthe following could be a valid explanation for what caused this change in synaptic strength? Assume baly one thing changed to cause these results . A larger number of aice yicholine (ACh) molecules were released from the synaptic vesicles A smaller number of acetylcholine (ACh) molecules were released from the synaptic vesicles c. There was an increase in the number of postsynaptic ACh receptors There was a decrease in the number of postsynaptc AcCh receptors There was an increase in the number of synaptic vesicles released when the presynaptic neuron was imulated There was a decrease in the number of synaptic vesicles released when the presynaptic neuron was stimulated Question 10: Which of the following variables is/are affected by the concentration of Ca? in the solution around the neuromuscular junction in these experiments? There may be more than one correct answer, select all that apply a. n C. q None of the above is affected by concentration of Ca2+

Explanation / Answer

9) e. There was an increase in number of synaptic vesicles released when the presynaptic neurons are stimulated.

This results in increase of synaptic strength. This synaptic vesicles release causes to change the postsynaptic density. Example: Ach is released from synaptic vesicles which is broken down in synaptic cleft by enzyme acetylcholinesterase and again choline is transported back to the axon so that it can produce more acetylcholine as acetyl CoA is released from mitochondria in axon and combine to form acetylcholine.

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