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inflamed aiiu ui chemotherapy, and the presence of infections, Sullu candidiasis

ID: 3506166 • Letter: I

Question

inflamed aiiu ui chemotherapy, and the presence of infections, Sullu candidiasis. Explain how this situation would affect food and fluid intake and list some possible subsequent effects on the patient with leukemia. CASE STUDY A Acute Lymphocytic Leukemia PM, aged 4 years, has returned to the family physician because of a recurrent sore throat and cough. Her mother mentions unusual listlessness and anorexia. The physician notices several bruises on her legs and arms and one on her back. The physician orders blood tests and a course of antibacterial drugs. Test results indicate a low hemoglobin level, thrombocytopenia, and a high lymphocyte count, with abnormally high numbers

Explanation / Answer

1) this is due to activation of protooncogene to oncogene and further activation of transcription factors.these process bring malignant transformation of lymphoblasts whose clonal proliferation replaces normal marrow cells and causes ALL.

2) anaemia,nutropenia and thrombocytopenia id due to bone marrow failure.

Fever is due to neutropenia.

Bruises is due to thrombocytopenia.

Low Hb is due to anemia.

3) blast cells production increases in ALL due to bone marrow failure and they starts appearing the blood which is seen in Smear.

4) Lymphoblasts which are malignant cells compete with normal cell for nutrition at the pace double than normal cells do.It can cause weight loss .