Given the following table Using the data above as the initial conditions in each

ID: 3506801 • Letter: G

Question

Given the following table

Using the data above as the initial conditions in each case, determine the effects of the following procedures on

the water and solute in the ECF and ICF after equilibrium has occurred. You should be able to give the

numerical values for volume and osmolarity of the ECF and ICF. Briefly explain your rationale for solving each

problem. (Treat each solution below as a separate problem; do not make them additive.)

Patient receives an intravenous infusion of 1.5 L of glucose solution containing 0.25 moles of glucose per liter

of solution. Calculate ECF and ICF volumes and osmolarity at the point where 1/3 the glucose has entered the

cells.

How will this change the table? and why?

Total ECF ICF Plasma Vol L 40 L 13 L 27 L 2.8 L Sol osmol 11.4 3.705 7.695 0.798 mOsM 285 285 285 285

a. Patient receives an intravenous infusion of 1.5 L of glucose solution containing 0.25 moles of glucose per liter of solution.

Total number of moles of glucose received

= 1.5*0.25

= 0.375 moles

So the volume of Total fluid, ECF and plamsa will increase by 1.5L

whereas, the number of moles of total moles, ECF and plamsa will increase by 0.375.

Osmolarity will also change respectively.

Hence, the new table is

When 1/3 rd of glucose has enetered the cells,

ie. 0.125 moles of glucose will enter the cells

hence, the further changes will be:

the moles of glucose will increase in ICF and will decrease elsewhere.

Volume increases and gets added up in the table.

Same goes for the number of moles.

Molarity depends on both of the above factors and hence, changes accordingly.

Quantity Total ECF ICF Plasma Vol L 41.5 L 14.5 L 27 L 4.3 L Sol osmol 11.775 4.08 7.695 1.173 mOsM 283.74 281.38 285 272.29

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