Dexamethasone is a drug used to suppress the secretion of ACTH from the anterior

Question

Dexamethasone is a drug used to suppress the secretion of ACTH from the anterior pituitary gland. Two patients with hypersecretion of cortisol are given dexamethasone. Anika's cortisol secretion level falls to normal after the medication, but Bonnie's cortisol secretion remains elevated. Which patient has primary hypercortisolism, also known as Cushing's disease, and why? a. Anika; because her cortisol levels returned to normal indicating the problem was in the 3. pituitary gland b. Bonnie; because her cortisol levels did not return to normal indicating the problem was in the pituitary gland c. Anika; because her cortisol levels returned to normal indicating the problem was in the adrenal gland d. Bonnie; because her cortisol levels did not return to normal indicating the problem was in the adrenal gland Synergism occurs when a. One hormone triggers the secretion of a second hormone b. One hormone inhibits the release of a second hormone c. Hormones working together produce a larger effect than predicted d. Hormones working together produce a smaller effect than predicted e. A hormone can exert its full effects only in the presence of another hormone The adrenal cortex produces Na and K' and it, also secretes a. Aldosterone; cortisol b. Cortisol; insulin c. Cortisol; glucagorn d. Aldosterone; insulin 4. hormone, which controls the absorption and secretion of hormone important for controlling blood glucose levels

Explanation / Answer

3b) Bonnie, because the level didn't return to normal indicating the problem was in the pituitary gland. The gland kept releasing ACTH which resulted in increased cortisol. Hence Cushing syndrome.

4 c) hormones working together produce larger effect than predicted.

5a) aldosterone and cortisol

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