Salivary amylase is released in the mouth where it breaks down sugars. However,

Question

Salivary amylase is released in the mouth where it breaks down sugars. However, it is inactive once it reaches the stomach where pH is quite low. Knowing the effect of pH on enzyme function, select all that describe why this happens.

A.Hydrogen ions in the stomach acid bind the enzyme.

B.Hydrogen ions are released from, the enzyme.

C.Change in hydrogen ions disrupts the electrostatic interactions within the enzyme molecule.

D.The enzyme may denature.

Salivary amylase is released in the mouth where it breaks down sugars. However, it is inactive once it reaches the stomach where pH is quite low. Knowing the effect of pH on enzyme function, select all that describe why this happens. Hydrogen ions in the stomach acid bind the enzyme. Hydrogen ions are released from, the enzyme. Change in hydrogen ions disrupts the electrostatic interactions within the enzyme molecule. The enzyme may denature.

Explanation / Answer

Hydrogen ion in stomach neutralise the negative charge on R group and disrupt the ionic interaction in the amylase activity and it causes the denaturation and change in active site of salivary amylase. Hence option C and D are correct.

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