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SECTION II-PHYSICAL EXAM etechiae occur with thrombocytopenia or severe platelet

ID: 3509204 • Letter: S

Question

SECTION II-PHYSICAL EXAM etechiae occur with thrombocytopenia or severe platelet dysfunction and is typically seen in dependent areas such as the lower extremities and under the breasts or, in a bedridden patient, the flanks. Purpura can occur with platelet disorders, coagulation abnormalities, or various non- hemostatic disorders. Weakening of the blood vessels or surrounding tissues, such as is seen in vitamin C deficiency, corticosteroid excess, Ehlers- can allow increased extravasation of blood causing purpura Danlos syndrome and old age, Which laborat tory tests would you order? Select all that would be indicated. Viral titers for an acute infection Thrombopoietin (TPO) levels Glucose level Complete Blood Count Peripheral smear Reticulocyte count Prothrombin time (PT) and acti D-dimer Platelet Function Analyzer (or PFA-100 or Platelet Function Screen) vated partial thromboplastin time (APTT) Chest X-ray Direct antiglobulin test (DAT) Quantitative immunoglobulins Bleeding time Lactic dehydrogenase (LDH) Viral titers for a chronic infection with HIV and hepatitis C Helicobacter pylori antigen assay

Explanation / Answer

Petichiae are resulted due to reduced platelet levels in the blood or thrombocytopenia and platelet dysfunctions. Purpura is another condition caused due to platelet dysfunction, coagulation abnormalities and nonhemostatic disorders. These conditions are identified by laboratoiry tests like complete blood count, peripheral smear, PT and APTT, platelet function analyzer, Bleeding time, viral titers for chronic infection and Hepatitis C, viral titer in acute infection and thrombopietin levels.