6. Using the ung compliance relationships for different diseases presented in th

Question

6. Using the ung compliance relationships for different diseases presented in the figure below, answer the following questions. 6 -2 -6 0.5 0 0 10 Inspiration Expiration Pressure (cm H20) (a) Using the plot on the right, what is the transpulmonary pressure at the (i) end of inspiration and (ii) end of expiration in cm H2O? (Hint: 1.36 cm H2O = 1 mmF1g) (b) Using the compliance plots for the different disease states on the right, and the transpulmonary pressures from (a), fill out the table below: Pathology Volume at the End of Inspiration (L) Volume at the End of Expiration (L) ida Vlume (L.) Asthma Cardiac Disease Fibrosis Respiratory Distress Syndrome Table 1: Tidal Volumes for Different Pathologies

Explanation / Answer

a) alveolar pressure - intrapleural pressure = transpulmonary pressure

i) at the end of inspiration = 0-(-6)= -6 mm of Hg

1/-6*1.36 cm H2O=0.226 cm H2O

ii) at the end it was -4 mm of Hg

1/4*1.36 = 0.34 cm H2O

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