Hemoglobin greatly affect’s an organism’s ability to transport oxygen in the blo

Question

Hemoglobin greatly affect’s an organism’s ability to transport oxygen in the blood. Describe any two factors that affect hemoglobin’s ability to bind to oxygen, being sure to address the following points:
-what the factors are an indicator of (1 mark per factor)
-how the factors change hemoglobin under high vs low metabolic demand (1 mark per factor)
-whether the factors skew hemoglobin’s saturation curve to the left or to the right (0.5 mark per factor)
Note: do not use partial pressures of gass as a “Factor”

Quick answers please

Explanation / Answer

several factors influence the oxygen binding capacity such as temparature,PH,Pco2, 2,3diphosphoglycerate.

1)2,3diphosphoglycerate:

it is a product formed from glycolysis in rbc.it reversibly bind to the haemoglobin and decrease the affinity of haemoglobin to oxygen binding.whenever the 2,3 BPG levels are increased in rbc it leads to unloading of oxygen.

during the high metabolic demand its concentration increases and it leads to unloading of oxygen.during low metabolic demand its concentration its conc decreases and increases the oxygen binding capacity.

it shifts the haemoglobin saturation curve to right side because the increased 2,3BPG leads to increased release of oxygen so po2 also rises.this leads to right shift of curve.

2)temparature

as temparature increases the oxygen binding capacity decreases and leads to release of oxygen.

in excercise condition the metabolic demand is increased.due to the high metabolicprocess og muscle the temparature increases leading to release of oxgen from haemoglobin and decrease the oxygen binding capacity.

as increase in temparature,oxygen release increase it leads to increased po2 levels so the curve shift to right

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