15.A naïve T cell refers to a T cell that: A. does not express CD4+ or CD8+. B.

Question

15.A naïve T cell refers to a T cell that: A. does not express CD4+ or CD8+. B. has not left the bone marrow C. has not yet encountered an antigen that it can bind. D. is not yet mature. E. resides in the thymic medulla. 16. What is the main role of Follicular helper T cells (TFH) cells? A. To help B cell development in germinal centers B. To regulate TREG cell activity C. To stimulate dendritic cell production D. To suppress B-cell activation after pathogen has been cleared E. To suppress Tc cells after an infection has been cleared 17. What is the function of a memory T cell? A. To activate Tc and TH cells during an active primary infection B. To avoid autoimmune disorders by producing memory for self-antigens during T-cell development C. To maintain an active T-cell response (Tc or TH) after an infection is cleared D. To provide an almost immediate response upon subsequent exposure to a specific pathogen E. To suppress Tc activity after a pathogen is cleared

Explanation / Answer

15) T cells are formed in bone marrow and migrate to thymus for the maturation process. A t cell which hasn't yet migrated thymus is definately immature. Therefore option B is correct.
16) ?T helper follicular cells are found in the secondary lymphoid organs in close proximity with B cells. They help the B cells in antibody production. Thus, option A seems correct here.
17) ?After the primary immune response has been completed, some T cytotoxic cells convert to memory t cells. Once converted, these help to provide an almost instantaneously secondary immune response on subsequent exposure to same pathogen. Thus option D seems correct here.

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