#5. In a research study, questionnaires were mailed to every 10th person listed
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#5. In a research study, questionnaires were mailed to every 10th person listed in the city telephone directory. Each person was asked to list age, sex, smoking habits, and respiratory symptoms during the preceding seven days. Over 90% of the questionnaires were completed and returned. Prevalence rates of upper respiratory symptoms were determined from the response (3 pts.) This is a type of study. #6. In a study to investigate the relationship between obesity and diabetes 75 pairs of twins were recruited where one twin was diabetic. They were then classified as Obese (BMI>30) or Not Obese (BMIs30) with data shown below. (6 pts.) Non Diabetis Noi-Obese Obese 48 Obese Diabetic Non-Obese 16 not (a) Do these data support a relationship between Obesity and Diabetes? Interpret your 14 results. (b) Instead or is pairs of twins, if our data came from 150 unrelated individuals, would weast come to the same conclusion? Support your conclusion with an unmatched analysis.n bese Was the recruitment of twins useful for this study? 48 ASExplanation / Answer
Yes it supports.Obesity is believed to account for 80 - 85% of the risk of developing type 2 diabetes, obese people are up to 80 times more likely to develop type 2 diabetes than those with a BMI of less than 22.
Inflammatory response - Abdominal fat causes fat cells to release pro inflammatory chemicals which can make the body less sensitive to the insulin it produces by disrupting the function of insulin responsive cells and their ability to respond to insulin.This is known as insulin resistance.
Disruption in fat metabolism - Obesity is also thought to trigger changes to the body's metabolism.These changes cause fat (adipose) tissue to release fat molecules into the blood, which can affect insulin responsive cells and lead to reduced insulin sensitivity.
Preventing obesity
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