Corneal transplants can be done using corneas harvested from cadavers and there

Question

Corneal transplants can be done using corneas harvested from cadavers and there is little chance of rejection once implanted. What feature of the cornea explains this?

Question 5 options:

A)

Corneas harvested from cadavers no longer have receptor present that will bind with immune cells from the recipient

B)

The cornea is part of the vascular tunic and its vascularity prevents rejection by the host

C)

The cornea is part of the fibrous tunic and therefore is avascular

D)

The cornea is resistant to immune cells from the host

A)

Corneas harvested from cadavers no longer have receptor present that will bind with immune cells from the recipient

B)

The cornea is part of the vascular tunic and its vascularity prevents rejection by the host

C)

The cornea is part of the fibrous tunic and therefore is avascular

D)

The cornea is resistant to immune cells from the host

Explanation / Answer

Option C is the correct answer. There are three tunics of the eye ball. These tunics are three concentric coverings. The first one is an external, fibrous tunic consisting of cornea and sclera; second one is middle, vascular tunic consisting of the iris, ciliary body, and choroid; and third one is internal nervous tunic (retina).

The fibrous tunic is avascular and therefore cornea and sclera is avasculur. Since cornea is avascular ther is no interaction of immune cells (immune privileged) involved in chornea transplantation and thus less ilkey to be rejected.

Note: Mostly rejection is occured due to interaction of immune cells (immunorejection).

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