Which of the following statements correctly differentiates the action of lisinop

Question

Which of the following statements correctly differentiates the action of lisinopril and irbesartan?

ACE inhibitors reduce the formation of bradykinin. Decreased levels of bradykinin induce a cough reflex. Irbesartan increases the action of angiotensin converting enzyme, thus producing elevated levels of bradykinin.

Lisinopril is an ACE inhibitor that prevents the conversion of angiotensin I to angiotensin II, in doing so it reduces blood pressure. Irbesartan is a statin that reduces the body’s natural production of cholesterol, thus treating hypercholesterolemia.

Lisinopril is an ACE inhibitor that prevents the conversion of angiotensin I to angiotensin II. Irbesartan prevents the binding of angiotensin II with the angiotensin receptor.

Lisinopril and irbesartan effectively work in the same way so would never be used together. The advantage of lisinopril is that it does not cause renal potassium retention and thus has no potential to cause hyperkalaemia, whereas irbesartan does retain potassium.

ACE inhibitors reduce the formation of bradykinin. Decreased levels of bradykinin induce a cough reflex. Irbesartan increases the action of angiotensin converting enzyme, thus producing elevated levels of bradykinin.

Lisinopril is an ACE inhibitor that prevents the conversion of angiotensin I to angiotensin II, in doing so it reduces blood pressure. Irbesartan is a statin that reduces the body’s natural production of cholesterol, thus treating hypercholesterolemia.

Lisinopril is an ACE inhibitor that prevents the conversion of angiotensin I to angiotensin II. Irbesartan prevents the binding of angiotensin II with the angiotensin receptor.

Lisinopril and irbesartan effectively work in the same way so would never be used together. The advantage of lisinopril is that it does not cause renal potassium retention and thus has no potential to cause hyperkalaemia, whereas irbesartan does retain potassium.

Explanation / Answer

Ans .. C

Lisinopril is an ACE inhibitor that prevents the conversion of angiotensin I to angiotensin II . Irbesartan prevents the binding of angiotensin II with the angiotensin receptor .

Lisinopril is ACE inhibitor that is angiotensin converting enzyme inhibitor . This enzyme helps in conversion of angiotensin I to angiotensin II.

Irbesartan is ARB that is angiotensin receptor blocker . It prevents the binding of angiotensin to its receptor .

Both these drugs helps in reducing the blood pressure .

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