niz I for Pharmacology (section 2) ???? (name ), Choose the one best answer I. L

Question

niz I for Pharmacology (section 2) ???? (name ), Choose the one best answer I. Long-term administration of glucocorticoids can induce the following adverse effects EXCEPT B. Hyperkalaemia C. Peptic ulcer D. Proximal myopathy E. Hyperglycemia Which of the 2. Glucocorticoids are powerful anti-inflammatory agents following is not an anti-inflammatory mechanism of action of glucocorticoids? A. Decrease secretion of proteolytic enzymes B. Reduction in the release of cytokines, such as II-1 and it-2 C. Inhibition of transcription of NF-kB D. Decreased number of circulation neutrophils E. Impairment of prostaglandin and leukotriene synthesis 3. The treatment of myxedema coma can include which of the following agents? A. Thyroglobulin

Explanation / Answer

ANSWER 1 : The long-term administration of gluocorticoides does not cause 'Hyperkalaemia' (increase K+ level) since, it is regulated by aldosterone (mineralocorticoides).

ANSWER 2 : The decrease in circulatory neutrophils is not an anti-inflammatory action of glucocorticoides. Since, these steroidal hormone (glucocorticoides) stimulate leucocytes(neutrophil) in the fluid circulation.

ANSWER 3 : A synthetic drug or agent "levothyroxine" can be use to treat comma due to myxoedema.

ANSWER 4 : The most dangerous adverse effect of administration of methimazole( a steroid) is Agranulocytosis ( increase production of agranulocytes).

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