D Student Matching With Synthetic Agglutination to Determine Blood Type The type
ID: 3523469 • Letter: D
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D Student Matching With Synthetic Agglutination to Determine Blood Type The type of antigons present on the surface of red blood cells cam bes determined by using what we know about antigon-antibody reactions. As stated above, when blood cells with a particular antigen are mixed with antibodles to that antigon, an agglutination reaction takes place causing the red b cells to clump together. In the following experiment, you will be mixing synthetic blood samples with synthetic antisera that contain antibodies to a particular antigen Anti-A antiserum contains anti-A antibodies that bind to erythrocytes with A antigens Anti-B antiserum contains anti-B antibodies that bind to erythrocytes with B antigens. Anti-Rh antiserum contains anti-Rh (anti-D) antibodies that bind to erythrocytes with the Rh factor (antigen D) The Rh type is often a, gton combined with the ABO type in a single expression such as O- for type O. Rh-positive, with or AB- for type AB, Rh-negative. Practice Before you begin the experiment, ensure that you understand the basis of blood typing and donor/recipient compatibility by completing the Table below. Genetics Blood Type Antibodies presentCan donate to:eve blood Antigens present) from: AA or AO BB or BO AB Rh Rh Obtain a blood typing kit and the accompanying worksheet from the front bench. Follow the instructions o the worksheet to complete the experiment, then answer the associated questions. When you are interpretiExplanation / Answer
Genetics
BLOOD TYPE
(ANTIGEN PRESENT )
ANTIBODIES PRESENT
CAN DONATE TO
CAN RECEIVE FROM
AA or AO
A
ANTI-B
A, AB
A, O
BB or BO
B
ANTI-A
B, AB
B, O
AB
A AND B
NONE
AB
A, B, AB, O
O
NONE
ANTI-A AND ANTI-B
A, B, AB, O
O
Rh-= A-
B-
AB-
O-
A
B
A&B
NONE
ANTI-B
ANTI-A
NONE
ANTIA AND ANTI-B
A+, AB+A-,AB-
B+, B-,AB+,AB-
AB+, AB-
EVERYONE
A-, O-
B-, O-
A-,B-,AB-,O-
O-
Rh+ = A+
B+
AB+
O+
A
B
A&B
NONE
ANTI-B
ANTI-A
NONE
ANTIA AND ANTI-B
A+, AB+
B+, AB+
AB+
A+, B+, AB+, O+
A+, A-, O+, O-
B+,B-, O+,O-
EVERYONE
O+, O-
Genetics
BLOOD TYPE
(ANTIGEN PRESENT )
ANTIBODIES PRESENT
CAN DONATE TO
CAN RECEIVE FROM
AA or AO
A
ANTI-B
A, AB
A, O
BB or BO
B
ANTI-A
B, AB
B, O
AB
A AND B
NONE
AB
A, B, AB, O
O
NONE
ANTI-A AND ANTI-B
A, B, AB, O
O
Rh-= A-
B-
AB-
O-
A
B
A&B
NONE
ANTI-B
ANTI-A
NONE
ANTIA AND ANTI-B
A+, AB+A-,AB-
B+, B-,AB+,AB-
AB+, AB-
EVERYONE
A-, O-
B-, O-
A-,B-,AB-,O-
O-
Rh+ = A+
B+
AB+
O+
A
B
A&B
NONE
ANTI-B
ANTI-A
NONE
ANTIA AND ANTI-B
A+, AB+
B+, AB+
AB+
A+, B+, AB+, O+
A+, A-, O+, O-
B+,B-, O+,O-
EVERYONE
O+, O-
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