9. Consider a disease-causing allele that is present at a frequency of 1% in hum
ID: 35303 • Letter: 9
Question
9. Consider a disease-causing allele that is present at a frequency of 1% in humans. For each of the following comparisons (a-c), indicate which of the two scenarios would lead to the mole rapid elimination of the allele from the population. Briefly explain your logic in each case. Scenario 1 a. The allele is recessive. b. The disease causes a 30% reduction in fertility. c. The disease increases mortality in children. Scenario 2 The allele exhibits incomplete dominance. The disease causes complete sterility. The disease increases mortality in the elderly.'Explanation / Answer
1. the allele that exhibits incomplete dominance will in the future leasd to the elimination of the allelic character in the population.
incomplete dominance is a type of dominance relationship between two alleles, individuals who are heterozygous Rr (R- red petals, r- white petals) exhibit a phenotype intermediate between individuals who are homozygous.
For example, if the outcome of a cross between a snapdragon with red petals (RR) and one with white petals (rr) the offspring in the F1 have pink petals (Rr). In this case neither of the alleles for flower color is completely dominant over the other. Therefore, individuals who are heterozygous have a phenotype unlike those with either set (parent red or parent white petal) of homozygous alleles.
2. the disease causes complete sterilitry, here the cghances of the next generation is completely ruled out. Thus, ther will be a complete elimination of the allelic tranmsfer.
3. tha disease increases mortality in children- this will ensure that thr alleles are not passed on to the next generation thus eliminating the alleles from the population at one point in time.
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