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1) DNA sequences derived from transposable elements are rare in the human genome

ID: 35732 • Letter: 1

Question

1) DNA sequences derived from transposable elements are rare in the human genome.

A)True

B)False

2) DNA glycosylases recognize and cleave phosphodiester bonds in DNA.

A)True

B)False

3) Most DNA lesions and incorporated errors eventually become mutations.

A)True

B)False

4) How can spontaneous mutations arise?

A) They can be induced by radiation and base analogs.

B) They can occur during DNA tautomeric shifts, depurination, and deamination.

They can occur during DNA replication and crossing over.

D)They can occur in the process of cell division, retrotransposon activity within genomes, and wobble mispairing.

E) All of the above can cause spontaneous mutations

5) Which of the following statements about DNA lesions (deletions and insertions) is not correct?

A)DNA deletion and/or insertion can cause frameshift mutations or in-frame mutations.

B)In-frame mutations occur when insertions and deletions involve any multiple of three nucleotides.

C)In-frame mutations are less likely to affect the phenotype than frameshift mutations.

D)In-frame mutations that add or remove only one amino acid may still affect the phenotype.

E)Frameshift mutations generally have more drastic effects on the phenotype than do substitutions.

A) They can be induced by radiation and base analogs.

B) They can occur during DNA tautomeric shifts, depurination, and deamination.

C)

They can occur during DNA replication and crossing over.

D)They can occur in the process of cell division, retrotransposon activity within genomes, and wobble mispairing.

E) All of the above can cause spontaneous mutations

5) Which of the following statements about DNA lesions (deletions and insertions) is not correct?

A)DNA deletion and/or insertion can cause frameshift mutations or in-frame mutations.

B)In-frame mutations occur when insertions and deletions involve any multiple of three nucleotides.

C)In-frame mutations are less likely to affect the phenotype than frameshift mutations.

D)In-frame mutations that add or remove only one amino acid may still affect the phenotype.

E)Frameshift mutations generally have more drastic effects on the phenotype than do substitutions.

Explanation / Answer

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