membrane potential. Consider the resting state of an excitable membrane of a hyp

Question

membrane potential. Consider the resting state of an excitable membrane of a hypothetical organism. Assume the organism and its surrounding contains impermeable macroions needed for charge neurtrality.

The Nernst potential for Na+ was found to be -2.81 mV and the Nernst potential for K+ was found to be 66.37 mV.

membrane potential. Consider the resting state of an excitable membrane of a hypothetical organism. Assume the organism and its surrounding contains impermeable macroions needed for charge neurtrality. The Nernst potential for Na+ was found to be -2.81 mV and the Nernst potential for K+ was found to be 66.37 mV. Question: assume there is a 1:4 Na+K+antiport pump acting to maintain a resting potential. In which direction are the ions pumped? Calculate the membrane potential

Explanation / Answer

In antiport pumps, the Na+ ions are diffused out of the cell, while K+ ions move in

At room temperature (20oC),

Vi Nerst for Na+ = - 0.6174 mV

Vi Nerst for K+ = 14. 56 mV

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