please help. I am super confused! I need help with questions 3 and 4. Please cho
ID: 37554 • Letter: P
Question
please help. I am super confused! I need help with questions 3 and 4. Please choose one answer for each!
QUESTION 3
DNA is taken from 3 brothers. Larry has cystic fibrosis (CF), Curly is a carrier of CF, and Moe is neither a carrier nor affected by CF. When we cut DNA from each of them with the restriction enzyme, StuI:
Larry's DNA doesn't cut at all (creates one 10kb band on a gel)
Curly's DNA creates three bands (10kb, 7kb, and 3kb)
Moe's DNA creates two bands (7kb and 3kb)
What can we say about the mutation that causes CF in this family?
-The mutation that causes CF disrupted/removed a restriction enzyme site that was normally present in the gene.
-The mutation that causes CF created a new restriction enzyme site in this gene.
-The mutation that causes CF did not change any StuI restriction enzyme sites in this gene.
-None of the above are true.
QUESTION 4
With regard to the previous question with Larry, Curly and Moe, what can we say about the genotypes of their parents with respect to CF?
One parent must have been homozygous dominant and the other homozygous recessive.
One parent must have been heterozygous and the other homozygous recessive.
Both parents must have been heterozygous.
Not enough information was given in the previous question to answer this.
-The mutation that causes CF disrupted/removed a restriction enzyme site that was normally present in the gene.
-The mutation that causes CF created a new restriction enzyme site in this gene.
-The mutation that causes CF did not change any StuI restriction enzyme sites in this gene.
--None of the above are true.
QUESTION 4
With regard to the previous question with Larry, Curly and Moe, what can we say about the genotypes of their parents with respect to CF?
One parent must have been homozygous dominant and the other homozygous recessive.
One parent must have been heterozygous and the other homozygous recessive.
Both parents must have been heterozygous.
Not enough information was given in the previous question to answer this.
Explanation / Answer
3. The mutation that causes CF disrupted/removed a restriction enzyme site that was normally present in the gene.
4. One parent must have been homozygous dominant and the other homozygous recessive.
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