For a population with a high frequency of NCRNA, propose a strategy for reducing

Question

For a population with a high frequency of NCRNA, propose a strategy for reducing the frequency of the disease? To answer this question you need to know:

-The NCRNA phenotype

-The mode of inheritance of the disease.

-The population that you need to screen, and the way you do it.

-The populations that you need to test and the way you do it.

-What reproductive plan would you suggest to a couple both heterozygotes for the NCRNA allele in order to help them to prevent the disease in their future kid(s).

Explanation / Answer

- NCRNA phenotype includes deficiency of various proteins. these non coding rna molecules do code for proteins but due to certain changes they are not translated.

mode of inheritance: automal recessive

population screened will include people suffering from diseases such as thalessemia, cancer, screening can be done by RNA sequencing.

reproductive plan for heterozygotic parents is that thye can use a sperm or ova donoralong with artificial insemination or in vitro fertilization of child.

they can have normal pregnancy followed by prenatal detection if the fetus carries the lcrna sequences.

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