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Would the child be affected (circle the correct answer)? Yes No Brief explanatio

ID: 40307 • Letter: W

Question

Would the child be affected (circle the correct answer)?   Yes   No

        Brief explanation:

The maps of the sites for restriction enzyme R in the wild type and the mutated cystic fibrosis genes are shown schematically in the following figure: Samples of DNA obtained from a fetus (F) and her parents (M and P) were analyzed by gel electrophoresis followed by the Southern blot technique and hybridization with the radioactively labeled probe designated CF probe in the previous figure. The auto radiographic results are shown in the following figure: Given that cystic fibrosis results [rom a recessive trait and affected individuals always have two mutant alleles, will the fetus be affected? Explain.

Explanation / Answer

No, the child would not be affected. This is because there is only one allele that is equal to the parental and materal. To get effected, the child should be heterogous with two alleles.

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