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Clathrin-coated vesicles are involved in recycling ofGolgi resident proteins dur

ID: 4070 • Letter: C

Question

Clathrin-coated vesicles are involved in

recycling ofGolgi resident proteins during cisternal maturation.

transport fromthe ER to the Golgi.

the uptake ofextracellular molecules by endocytosis and the transport ofmolecules from the trans Golgi network to thelysosomes.

the retrieval ofER resident proteins from the cis Golgi or the ER-Golgiintermediate compartment.

Clathrin-coated vesicles are involved in

recycling ofGolgi resident proteins during cisternal maturation.

transport fromthe ER to the Golgi.

the uptake ofextracellular molecules by endocytosis and the transport ofmolecules from the trans Golgi network to thelysosomes.

the retrieval ofER resident proteins from the cis Golgi or the ER-Golgiintermediate compartment.

Explanation / Answer

+C. the uptake of extracellular molecules by endocytosis andthe transport of molecules from the trans Golgi network tothe lysosomes. +Clathrin facilitates the formation of small vesicles in thecytoplasm. Clathrin-coated vesicles selectively sort cargo at thecell membrane, trans-Golgi network and endosomal compartments formultiple membrane traffic pathways. After a vesicle buds into thecytoplasm the coat rapidly disassembles allowing the clathrin torecycle while the vesicle gets transported to a variety oflocations. Adaptor molecules are responsible for self assembly andrecruitment
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