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Niremberg used the enzyme polynucleotide phosphorylase to assemble RNAs with ran

ID: 40764 • Letter: N

Question

Niremberg used the enzyme polynucleotide phosphorylase to assemble RNAs with random sequences in the absence of a template. Suppose they added the enzyme to a solution of 90% GTP and 10% UTP, and then use a cell-free system of protein synthesis to make peptides according to the sequences in their sysnthetic RNAs. and then a) Which amino acids could possible appear in the synthetic protein? b) Which amino acid would be the most abundant in the synthetic protein? c) Which amino acid would be least abundant?

Explanation / Answer

most abundant: glycine,

followed by valine

lest abundant: phenylalanine

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