One of the most difficult aspects of signaling through pathways that involve pro
ID: 41314 • Letter: O
Question
One of the most difficult aspects of signaling through pathways that involve proteolysis is keeping track of the names of the components and their functions. Sort the following list of proteins into the Notch, Wnt/B-cetenin, and Hedgehog signaling pathways, list them in he order they function, and select one or more appropriate descriptors that identify their role.
Protein
A. B-catenin
B. Cubitus interruptus )Ci)
C. Delta
D. Dishevelled
E. Frizzled
F. Glycogen sythase kinase 3 (GSK3)
G. Hedgehog
H. iHog
I. LRP
J. Notch
K. Patched
L. Presenilin
M. Smoothened
N. Rbpsuh
O. Wnt
Function (Type of protein)
1. Amplifier
2. Anchoring
3. Extracellular signal
4. Gene regulatory
5. Integrator
6. Latent gene regulator
7. Modulator
8. Protease
9. Receptor
10. Relay
11. Scaffold
12. Transducer
Explanation / Answer
Notch
C. Delta
D. Dishevelled
F. Glycogen sythase kinase 3 (GSK3)
J. Notch
N. Rbpsuh
Wnt/B-catenin
A. B-catenin
E. Frizzled
I. LRP
L. Presenilin
O. Wnt
Hedgehog
B. Cubitus interruptus )Ci)
G. Hedgehog
H. iHog
K. Patched
M. Smoothened
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