Need help summarizing all the main points of this research medical journal artic

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Need help summarizing all the main points of this research medical journal article

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Abstract

Objective The prevalence of obesity and associated cardiometabolic

risk factors such as diabetes, hyperlipidemia

and hypertension is increasing significantly for all demographic

groups.

Research design and methods The 2000 and 2002 Medical

Expenditure Panel Survey (MEPS), a nationally

representative survey of the U.S. population, was used to

estimate the marginal impact of obesity on health function,

perception, and preferences for individuals with diabetes,

hyperlipidemia, and hypertension using multivariate

regression methods controlling for age, sex, race, ethnicity,

education, income, insurance, smoking status, comorbidity,

and proxy response. Three different instruments were used:

SF-12 physical component scale (PCS-12) and mental

component scale (MCS-12); EQ-5D index and visual

analogue scale (VAS). Censored least absolute deviation

was used for the EQ-5D and VAS (due to censoring) and

ordinary least squares (OLS) was used for the PCS-12 and

MCS-12.

Results After controlling for sociodemographic characteristics,

diabetes, hyperlipidemia, and hypertension were

associated with significantly lower scores compared to

normal weight individuals without the condition for all four

instruments. Obesity significantly exacerbated this

association. Controlling for comorbidity attenuated the

negative association of obesity and cardiometabolic risk

factors on instrument scores. In addition, scores decreased

for increasing weight and number of risk factors.

Conclusions Obesity significantly exacerbates the deleterious

association between diabetes, hyperlipidemia, and

hypertension, and health function, health perception, and

preference-based scores in the United States.

Keywords Diabetes _ Health-related quality of life _

Hyperlipidemia _ Hypertension _ Obesity

Background

There is an epidemic of obesity in the United States and

much of the world [1

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