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Using the patch clamp technique, a researcher measures a single channel in a mem

ID: 42186 • Letter: U

Question

Using the patch clamp technique, a researcher measures a single channel in a membrane. The receptor channel passes 3 pA (picoamperes) of ionic current over a period of 8 msec at -60 mV; 1 pA = 10 -12 ampere.

Based on your knowledge of nerve transmission, this movement of ions will

A. stimulate a change in a postsynaptic membrane if 50 channel events are combined.
B. stimulate a change in a postsynaptic membrane if three channel events are combined.
C. not stimulate a change in a postsynaptic membrane.
D. generate a current resulting in membrane depolarization.
E. stimulate a change in a postsynaptic membrane

Explanation / Answer

Based on the given data, the receptor channel passes 3 pA (picoamperes) of ionic current over a period of 8 msec at -60 mV; 1 pA = 10 -12 ampere. So, this movement of ions will generate a current resulting in membrane depolarization. Thus, the correct option is (D).