The graph to the right shows the observed survival rate of C57BL/6 mice that wer

Question

The graph to the right shows the observed survival rate of C57BL/6 mice that were intraperitoneally injected with Yersinia enterocolitica. Two different Y. enterocolitica strains were examined that differed only in the IcrV gene sequence. One strain contained the wild-type IcrV allele (IcrVwr), the other contained a mutation thatchanged the 42nd amino acid from a lysine (K)to a glutamine (Q) (,lcrVK42Q.). Furthermore,two different doses of bacteria wereadministered, either 5 times 103 cfu or 104 cfu. What does this experiment seek to measure. Growth curve of two strains of Y. enterocolitica Relative virulence of two strains of Y. enterocolitica Susceptibility of two strains of mice Antibiotic susceptibility of two strains of Y. enterocolitica The smallest dose of Y. enterocolitica needed to cause disease Which Y. enterocolotica strain is attenuated ? lcr VWT strain lcr VK42Q why does the survival rate stop decreasing after about a week's time ? (Hint: think what happens inpeople who get serious disease and then get better instead of dying) True or False. The IcrV gene contributes to virulence ?

Explanation / Answer

10. B

11. B

12. This happens as over time the body modulates according to the invasive microorganism and helps stimulate more antibody production against it due to which better immunity is formed. This leads to the result that survival rate stops declining. after a week's time.

13. True

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