What is the obvious mistake made in the question posted below? What is wrong? Yo

Question

What is the obvious mistake made in the question posted below?

What is wrong? You are challenged by Dr. Dorsam about a newly discovered surface protein on a T cell called lmmunologyclassisalmostdone, or (ICAD). Dr. Dorsam gives you the following table of data he collected from performing a T cell activation experiment in a petri dish. To this petri dish, he added: 1. A mouse T cell hybridoma specific for a 45 amino acid peptide that is part of the protein called lloveimmunology, (ILIM) 2. Mouse dendritic cells (expressing B7-1 and B7-2) 3. The ILIM peptide 4. Media to keep the cells alive 5. One of five monoclonal antibodies or a polyclonal of all five (See table) He then tells you ICAD has amino acid sequence similarity to molecules that bind CD8OICD86. Lastly, these mice were CD28 knock outs.

Explanation / Answer

Mice cannot be CD 28 knock out , if they were they would not be able to interact with B71 or B72 .

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