Which one of the following statements concerning the citric acid cycle is correc

Question

Which one of the following statements concerning the citric acid cycle is correct?

A. The cycle produces three moles of NADH and one mole of FADH2 per mole of acetyl CoA oxidized to CO2 and H2O

B. The cycle is inhibited by malate.

C. Elevated levels of NADH stimulate oxidation of acetyl CoA by the cycle.

D. The oxidation of acetate leads to a net consumption (loss) of oxaloacetate.

E. The conversion of one mole of isocitrate to one mole of succinate results in the formation of five moles of ATP (including those obtained from oxidative phosphorylation).

Explanation / Answer

Citric acid cycle

Of the given statements, the true statement regarding citric acid would be,

A. The cycle produces three moles of NADH and one mole of FADH2 per mole of acetyl CoA oxidized to CO2 and H2O

E. The conversion of one mole of isocitrate to one mole of succinate results in the formation of five moles of ATP (including those obtained from oxidative phosphorylation).

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