Effects of Inhibitors L-arabinose is a caloric sweetener that acts as a non-comp

Question

Effects of Inhibitors L-arabinose is a caloric sweetener that acts as a non-competitive inhibitor of the enzyme sucrase. If L-arabinose is consumed, what wi happen to naturally occurring, non-c the hydrolysis of sucrose? Sucrose will continue to be hydrolyzed in small amounts. It will compete with L-arabinose for access to the sucrase active site. O Sucrose hydrolysis will be greatly reduced, since L-arabinose binding to sucrase will inactivate the enzyme O Sucrose hydrolysis will be greatly reduced, since all sucrase active sites will be occupied by L-arabinose Sucrose hydrolysis wi crease, since L-arabinose creases the efficiency of sucrase. L-arabinose consumption wi have little effect on the hydrolysis of sucrose

Explanation / Answer

The L-arabinose inhibits the enzyme sucrase by an uncompetitive inhibition method. The 4 percent of intake of L-arabinose inhibits sucrase activity, decreases postprandial glucose, insulin, and C-peptide responses and enhances GLP-1 responses. The inhibitor L-arabinose binds with enzyme-substrate complex to inhibit sucrase activity. The inhibitor forms enzyme-inhibitor-substrate complex.

Hence, the answer for the given question is sucrose hydrolysis will be greatly reduced, since L-arabinose binding to sucrase will inactivate the enzyme.

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