Hint-use mass fraction for other ingredients, calculate their masses in a pill.

Question

Hint-use mass fraction for other ingredients, calculate their masses in a pill. L-deprenyl (C13H17NHCI) is shown to prevent the metabolism of dopamine in the brain. With increased dopamine availability in the brain, the may subside. Cowboy Pharma wants to manufacture pills symptoms of Parkinson's disease containing L-deprenyl. However, the dosage of the active ingredient needed in a pill is only very small. In order to make larger tablets that can be handled, Pharma wants to use inert ingredients to make 200 mg pills. Inert ingredients are lactose (C12H220D, magnesium stearate and The mass fractions of lactose and magnesium stearate are 0.475 and 0.125 respectively. For this purpose, milligram of required per pill is O 7.5mg 65mg O 70mg O 75mg

Explanation / Answer

Mass fraction of lactose = mass of lactose/ mass of lactose+mass of Mg stearate

Mass fraction of Mg stearate= mass of Mg stearate/ mass of lactose+mass of Mg stearate

Assume the mass of the total integredents is 200 mg.

Mass of the lactose=0.475*200mg=95 mg

Mass of Mg stearate=0.125*200 mg=25 mg

Mass of total ingredients=mass of cellulose+mass of lactose+Mass of Mg stearate+Mass of active dosage ingredient

200 mg-95 mg-25 mg-5 mg=mass of cellulose=75 mg

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