Jack and Jill are thinking about starting a family and they come to you with a q

Question

Jack and Jill are thinking about starting a family and they come to you with a question about a rare recessive genetic diesease called Alpers Syndrome. Aplers causes progressive neurodegeneration in infants and children and is usually lethal within the first 10 years of life. Jack's grandfather had a brother die of Alpers Syndrome, while Jill has no family hisotry of the disease. If the frequency of herozygotes for Alpers is 1 in 2000 in the population, what is the chance that Jack and Jill will have a child with Alpers Syndrome?

Explanation / Answer

Alper

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