EXPERIMENT 19 Rolai An Analysis of Commercial Antacids Seltzer OBJECTIVES Determ

Question

EXPERIMENT 19 Rolai An Analysis of Commercial Antacids Seltzer OBJECTIVES Determine the per gram neutralizing ability of a commercial antacid Determine the per gram neutralizing ability of sodium bicarbonate Compare the effectiveness of several antacids. INTRODUCTION "How do you spell relief?" The parietal cells in the stomach secrete sufficient hydrochloric acid to normally keep the acidity at about 0.10 M. The flow of HCI increases when food enters the stomach and so acidity increases when you eat or drink. Ifoverstimulation of gastric juices builds the concentration up too much, heartburn or indigestion often results. Sodium bicarbonate (NaHCO3 in baking soda) has historically been used to try to relieve this condition. Today we have a number ofcommercial products which purport to neutralize (or buffer) excess stomach acid. Television commercials claiming greater effectiveness in neutralizing acid are familiar. Rolaids claims to consume 47 times its weight in excess stomach acid. Tums claims to have one third more neutralizing power than other antacids. In this lab, we will compare acid- neutralizing capabilities for ourselves. Several types of commercial antacids will be tested and the results will be shared in class. Keep in mind that tablets may also contain flavors, sweeteners, binders, fillers, antifoam agents, pain relievers, etc. In this experiment, the tablets will be analyzed only for their ability to neutralize acids. The active ingredient in antacids varies with the brand. The table below lists active ingredients in several brands. COMMERCIAL ANTACIDS MAJOR ACTIVE INGREDIENTS Brand Active Agent Milk of Magnesia. Mg(OH)2 Rolaids NaAl(OH)2CO, Tums Alka Seltzer NaHCO3 and KHCO3 Maalox. Mg(OH and Al (OH)3 Gaviscon Al(OH)3 The H (actually H30) from acids are neutralized by these agents as illustrated below: insoluble carbonates: Caco3(s) 2 H (aq) (aq) H20 co2(g) Can soluble bicarbonates: Hoos(aq) H (aq) H2o) co, g) Mg(OH)2(s) 2 H (aq)

Explanation / Answer

NaHCO3 is used as antacid after mixing with water,it reacts with HCl acid produced in stomach to form Sodium chloride salt,Carbondioxide & Water.
Stoichiometric equation of sodium bicarbonate reaction with acid is given below;

NaHCO3+HCl------>NaCl+H20+CO2

1 mole of sodium bicarbonate reacts with one mole of acid,based on this equation we can find out stoichiometric relations.

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