Which of the following acids will have the weakest conjugate base? Acetone, pk_a

Question

Which of the following acids will have the weakest conjugate base? Acetone, pk_a = 1.8 Acetylacetone, pk_a = 10 Acetic acid, pk_a = 4.7 HCN, pk_a = 9.2 Complete the following by circling on answer: A strong acid will have a strong conjugate base. The conjugate base of a strong acid will be a good/poor leaving group. The conjugate base of a weak acid will be a strong/weak nucleophile. A weak conjugate base will be a good/poor nucleophile A substitution reaction will be favorable if it involves a strong/weak nucleophile and a good/poor leaving group. Assign any formal charges in the following structure. Circle the strongest acid in each set below:

Explanation / Answer

8.

Acetic acid is having lower pka value among given acids, it is stronger acid. Its conjugate base will be weaker.

1. The strong acid will have weak conjugate base.

2. Conjugate base of strong acid will be good leaving group.

3. Conjugate base of weak acid will be strong nucleophile.

4. Weak conjugate base will be weak nucleophile.

5. A substitution reaction will be favourable if it involves strong nucleophile and good leaving group

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