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help 5-9 happen to the allele frequencies after 10 generations? 5. Since few peo

ID: 48724 • Letter: H

Question

help 5-9 happen to the allele frequencies after 10 generations? 5. Since few people with sickle cell anemia (SS) are likely to survive to have children of their own, why hasn't the S allele been eliminated from the population? Wh 6. y is the frequency of the sickle cell allele so much lower in the United States than in frica? What impact might a vaccine against malaria have on the frequency of the Sickle Cell allele in Africa in the long run? 7. There is evidence to suggest that heterozygotes might have an advantage during a malarial infection. Some think this may be due to the increased pressure on cells to sickle during infection. Describe how the sickled cells might allow the infection to be managed. You may use the Internet as a source, but be sure to cite your source and do not plagiarize 8. What is an allele frequency and how does it relate to evolution? Does understanding allele frequencies change your view of evolution? Does evolution occur with a single directionality? Explain in relation to this experiment. heterozygote has a selective advantage and therefore a fitness of W12-1. Assume the homozygotes have a fitness of W1 0.4 and W22 0.1, respectively. Calculate the allele frequencies after two rounds of selection. How do these calculations compare to the data you collected and the fitness values of the experiment? 9. The allele frequencies of the parents in our simulation were p 0.75 and q-0.25. The

Explanation / Answer

5.
S allele is not been eliminated Because sickle cell anaemia is not a lethal disease for the hybrid ones which means the ones who only carries this genes but does not show signs of disease. Even though sick ones may get older and have children's. therefore when a sick person or a carrier have children's, the gene is transmitted to the progeny.


6
Sickle cell is assumed to be the outcome of a genetic mutation which is caused by continual exposure by malaria over most generations. cells which are curved, instead of red blood cells which are round, are less of an appealing host to the Plasmodium Vivax : (Malaria) disease because of their form, and can protect against it more simply. People of African descent thus, due to the commonness of the disease on that continent, are more probable to inherit this mutation.

7.   
Believable evidence indicates, in areas with constant malaria  outbursts, individuals with the heterozygous state have a discrete advantage (and because of which individuals with heterozygous alleles are more common in areas).Those with the benign sickle trait retains a resistance to malarial infection. The pathogen which causes the disease spends part of its cycle in the red blood cells and initiates an abnormal drop in levels of oxygen in the cell. In the carriers, this drop is sufficient to initiate the full sickle-cell reaction, that leads to infected cells being fastly removed from circulation and strongly limiting the progress of infection. particular individuals have a high resistance to infection & have a higher chance of surviving outbursts. while, those with 2 alleles for SCA may persist malaria, but will die from their genetic disease unless they have way in to advanced medical care. Those of the homozygous  wild-type  or "normal" case will have a higher chance of passing on their genes victoriously, in that there is no possibility of their offspring's suffering from SCA; still, they are more liable to dying from malarial infection prior they have a chance to pass on their genes.


8.
It is defined as the percentage of all the alleles at a specified locus in a population gene pool characterized by a specific allele . Evolution is the change in frequencies of allele in a population in time , hence , change in the allele frequencies is the description of evolution.