1)Ordered: Cardizem 20mg IV for a rapid ventricular rate. Available: Cardizem 5
ID: 487399 • Letter: 1
Question
1)Ordered: Cardizem 20mg IV for a rapid ventricular rate. Available: Cardizem 5 mg/mL after reconstitution. Literature recommends giving each single dose over 2 minutes. What is the total mL to be injected?
2)This is a 2 answer problem: Ordered: Granisetron hydrochloride injection (Kytril) 10 mcg/kg IV injection 30 minutes before chemotherapy to reduce nausea and vomiting. Available: Kytril vial IV 0.1 mg/mL/ Patient weight 60kg. The nurse adds 2.4 mL of sterile normal saline for injection to the medication for ease of timing the injection rate into the injection port. What is the total dose of drug in mg to be given? 1 What tis the total volume of the drug for injection? 2
3)Ordered: Isoproterenol (Isuprel) IV inufsion 120 mcg/hr for a patient with coronary artery disease. IV solution at bedside: Isuprel 1mg in 500mL of D5W infusing at 50 mL per hour. How many mL/hr are ordered?
4)Ordered: Nicardipine hydrochloride IV 1.2mg/hr for a patient with hypertension. IV solution at bedside: 25mg Nicardipine in 500 mL of normal saline infusing at 24 mL/hr. What is the mL per hour ordered flow rate for this solution?
5)Calculate the hourly IV flow rate: The IV for a patient in critical care is flowing at 12 mL/hr. Ordered: 0.2mg per minute. IV: 500mg in 1000mL. Is the flow rate correct? If not, what should it be?
6)Calculate the hourly IV flow rates. Total drug: 100mg, Total volume: 100 mL, Hourly drug ordered: 4mg. What is the hourly volume (flow rate) (mL per hour to the nearest tenth of a mL).
7)5mcg per kg per min =_________mcg/hr. Weight: 30kg
8)Calculate the hourly IV flow rates. Ordered: An IC of 2 mcg per kg per minute. Available: The pharmacy-prepared IV contains 100mg in 250 mL. Patient weight: 50 kg. How many mL/hr are needed to the nearest 10th of a mL?
9)Ordered: Dopamine IV at 4 mcg/kg/min. SDR: 2-10mcg/kg/min. IV is flowing at 10 mL/hr. Patient weight is 60 kg. Is the order within SDR?
10)10 mcg per kg per min =_______mcg/hr. Weight 75 kg
Explanation / Answer
1) Let x mL of Cardizem 5 mg/mL solution be injected to attain a total dose of 20 mg.
Mass of Cardizem in x mL of the solution = (x Ml)*(5 mg/1 mL) = 5x mg.
Therefore, 5x = 20
===> x = 20/5 = 4
Therefore, 4 mL of Cardizem 5 mg/mL solution must be injected (ans).
2) You have Granisetron Hydrochloride injection (Krytil) 10 mg/kg.
Patient weight is 60 kg.
Therefore, dose of Krytil 10mg/kg required = (10 mg/kg)*(60 kg) = 600 mg (ans).
Krytil vial IV 0.1 mg/mL is available. Let the total volume required be V mL. Then the dose of Krytil administed = (V mL)*(0.1 mg/mL) = 0.1*V mg.
As per the problem,
0.1*V = 600
===> V = 600/0.1 = 6000/1 = 6000
The total volume of drug required = 6000 mL = 6 L (since 1 L = 1000 mL) (ans).
3) Ordered: Isuprel IV infusion 120 mg/hr.
Available: Isuprel solution 1 mg in 500 mL infusing at 50 mL/hr.
Find out the mass of Isuprel solution injected in mg/hr as (50 mL/hr)*(1 mg/500 mL) = 0.1 mg/hr.
Let the dosage required be x.
Therefore,
(0.1*x mg/hr) = 120 mg/hr
===> x = 120/0.1 mg/hr = 1200/1 mg/hr = 1200 mg/hr (ans).
4) Ordered: Nicardipine Hydrochloride IV 1.2 mg/hr.
Available: Nicardipine solution 25 mg in 500 mL infusing at 24 mL/hr.
Mass of Nicardipine solution infused = (24 mL/hr)*(25 mg/500 mL) = 1.25 mg/hr.
Let x ml/hr be the required medication.
Therefore, 1.25x mg/hr = 1.2 mg/hr
===> x = 1.2/1.25 = 0.96
0.96 mL/hr of medication must be prescribed (ans).
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