Which of the following mRNAs would be degraded the most rapidly? an mRNA with 20

Question

Which of the following mRNAs would be degraded the most rapidly?

an mRNA with 200 adenine residues at its 3' end

an mRNA with multiple AAUUU sequences in its 3' untranslated region and with 200 adenine residues at its 3' end

an mRNA with 100 adenine residues at its 3' end

an mRNA with multiple AAUUU sequences in its 3' untranslated region and with 10 adenine residues at its 3' end

an mRNA with 200 adenine residues at its 3' end

an mRNA with multiple AAUUU sequences in its 3' untranslated region and with 200 adenine residues at its 3' end

an mRNA with 100 adenine residues at its 3' end

an mRNA with multiple AAUUU sequences in its 3' untranslated region and with 10 adenine residues at its 3' end

Explanation / Answer

The option is B. The presence of AAUUU residues in the 3' untranslated region brings stability to the mRNA. The presence of a longer segment of polyA residues also increases the stability and life of the mRNA. Hence, the options (a) and (c) are wrong because the 3'-UTR is absent in the mRNA. The option (d) is also wrong since only 10 adenine residues are present at the end of the mRNA.

Hence, the correct option is B.

Related Questions

Navigate

• Browse (All)
• Browse W
• Subjects

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.