While working in Thomas Hunt Morgan\'s lab, Alfred Sturtevant developed and used

Question

While working in Thomas Hunt Morgan's lab, Alfred Sturtevant developed and used a method to order and map distances between linked genes. You are going to use this method to map the following genes: curly wings (cy), vestigial wings (vg), vermillion eyes (v) and stubble bristles (sb). A true breeding curly, vestgial winged female fly is crossed with a stubble bristle, vermillion eyed male fly and all of the progeny are wild-type. The F1 tetrahybrid is then crossed with a fly that is homozygous recessive for all four loci and the following data is produced:

cy sb vg v 2
cy + vg + 536
+ sb vg v 19
cy sb + v 94
+ + + + 1
+ + + v 9
+ sb vg + 49
cy + vg v 116
+ sb + v 501
cy + + v 43
+ + vg + 88
+ sb + + 109
+ + vg v 24
cy + + + 17
cy sb vg + 11
cy sb + + 26

Explanation / Answer

location of the gene can be determined as

we must first identify the parental type , those will be genotype with maximum number of out comes

cy + vg + 536 and + sb + v 501

and the two smallest one are + + + + and cy sb vg v

so on common basis sequence will be cy+vg+sbv

this will be the sequence as determined by the correlation between the two.

we have taken these two becaue in minimum and maximum thye always try to retain there original sequence

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