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Why is there a need to produce Okazaki fragments on thelagging strand but not on

ID: 4951 • Letter: W

Question

Why is there a need to produce Okazaki fragments on thelagging strand but not on teh leading strand of DNA A. The two parental strands of DNA are antiparallel and DNApolymerase makes DNA in the 5' to 3' direction only B. it is faster to make several smaller fragments thanone larger fragment D. it is substantially more efficient to make several shorterstrands rather than one longer strand of DNA E. By having one leading strand and one lagging strand thecell can limit the amount of DNA polymerase used for chromosomalreplication F. There lacks enough cellular DNA ligase for bonding Okazakifragments together if they were produced from both parentalstrands Why is there a need to produce Okazaki fragments on thelagging strand but not on teh leading strand of DNA A. The two parental strands of DNA are antiparallel and DNApolymerase makes DNA in the 5' to 3' direction only B. it is faster to make several smaller fragments thanone larger fragment D. it is substantially more efficient to make several shorterstrands rather than one longer strand of DNA E. By having one leading strand and one lagging strand thecell can limit the amount of DNA polymerase used for chromosomalreplication F. There lacks enough cellular DNA ligase for bonding Okazakifragments together if they were produced from both parentalstrands

Explanation / Answer

The answer is A. The lagging strand template is in the wrong direction of5'-3'. hence for replication, the DNA polymerase needs tosynthesise in okazaki fragments. The leading strand template is in the right direction of 3'-5'and hence the replication can go on in the 5'-3' direction.
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