In most fatal cases of aspirin poisoning, the dosage has been greater than 20 gr

Question

In most fatal cases of aspirin poisoning, the dosage has been greater than 20 grams. How many aspirin tablets are necessary to supply 20 grams of aspirin? _____ Calculations: The toxicity of a substance is usually given in the form "LD_50 (method of dosage) in (test specie): x mg/kg (of body weight)." For example, for salicylic acid, The Merck Index gives: LD_50 i.v. in mice: 500 mg/kg. "I.v." means intravenous, by injection into a vein. The LD_50 must be known when prescribing medicines; to be effective, their doses often have to approach levels at which they may become toxic, and the physician has to know what that level is. If salicylic acid toxicity were the same for humans as for mice and a person weighs 132 lbs, what percentage would a 10 g dose be of the LD_50 dose? [Show your calculations.] Why do the textures of different brands of aspirin tablets differ? Aspirin relieves the symptoms of head colds by reducing fever and easing aches and pains does not shorten the time needed to "get over" the cold. Some physicians have that aspirin may actually lengthen the period of a cold. Why might aspirin have effect?

Explanation / Answer

Mass of one tablet of aspirin = 325mg =0.325g

So number of tablets in 20g os aspirin = 20/0.325 =61.538

S ince we cannot give 61.538 tablet so by rounding it off we get 62 tablets.

Related Questions

Navigate

• Browse (All)
• Browse I
• Subjects

---

---

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.