2. (2pt) Abe and Claris Norman had an abnormal child that died shortly after bir

Question

2. (2pt) Abe and Claris Norman had an abnormal child that died shortly after birth. At the birth of the child, the Normans met with a genetic counselor who took tissue samples from the child before it died. The counselor prepared metaphase chromosome spreads of the sample and found cytogenetic differences between the child's chromosome 22 pair. The counselor then prepared metaphase chromosomes from both parents. The chromosome 22 spreads for both parents and the child are shown below a) Do the parents have an abnormal chromosome 22, and if so which parent(s) and what is the nature of the abnormality (be specific)? b) How did the child's abnormal chromosome arise? Why did he die? c Advise this couple. Can they have normal children? How likely are they to have more abnormal children? Abe Claris child

Explanation / Answer

yes parents have abnormal chromosome 22.

there is a deletion in the part of chromosome 22, which leads to Di georges syndrome.

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