How do I determine the Ka value of a buffer solution mixed with creatine hcl? *T
ID: 499934 • Letter: H
Question
How do I determine the Ka value of a buffer solution mixed with creatine hcl?*The buffer itself contains 50mL (0.1M) acetic acid and 9.3mL (0.1M) sodium hydroxide. Then 50mL of that mixture is diluted in 950mL of deionized water to form a 1Liter buffer solution. One serving of the creatine hcl is dissolved 100mL from the 1L buffer that was made. How do I determine the Ka value of a buffer solution mixed with creatine hcl?
*The buffer itself contains 50mL (0.1M) acetic acid and 9.3mL (0.1M) sodium hydroxide. Then 50mL of that mixture is diluted in 950mL of deionized water to form a 1Liter buffer solution. One serving of the creatine hcl is dissolved 100mL from the 1L buffer that was made.
*The buffer itself contains 50mL (0.1M) acetic acid and 9.3mL (0.1M) sodium hydroxide. Then 50mL of that mixture is diluted in 950mL of deionized water to form a 1Liter buffer solution. One serving of the creatine hcl is dissolved 100mL from the 1L buffer that was made.
Explanation / Answer
Ka of a weak acid is a fixed term. It does not matter how much NaOh or HCl u add,Ka will remain constant.
Ka of a buffer can be calculated from :
pH = pKa + log [salt/acid]
once you know the pH and the moles of salt (sodium acetate) and acid (acetic acid) present, you can calculate pKa from the above equation . Ka = 10^-pKa
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