1. Formation of Chromatin Loops in the nucleus might result in A. Transcriptiona

Question

1. Formation of Chromatin Loops in the nucleus might result in

A. Transcriptional activation

B. Transcriptional repression

C. Epigenetic Regulation

D. Long range genomic interactions

E. All of the above

2. Which of the following statements is false?

A. All the muscle cells in human body express MyoD

B. All the cells in human body express MyoD and a few homeotic genes

C. MyoD protein can transform few differentiated cells into muscle cells

D. Pattern formation is controlled by specific genes

E. Morphogens are molecules that affect cell fate by their differential expression

8. Which of the following questions could NOT be answered by the process of RNA

interference (RNAi)?

A. What is the function of gene OSU in a particular species of a spider?

B. What will happen in a particular insect's digestion if gene OHO is not able to be translated?

C. Is gene MICH expressed in individuals for a disorder in humans?

D. Will the disabling of gene NEIL in Drosophila and in a mouse cause similar results?

E. None of the above

Please explain your answers.

Explanation / Answer

FORMATION OF CHROMATIN LOOP IN NUCLEUS RESULT IN ;

CHROMATIN LOOPS ARE THE STRUCTURES WHICH ARE PRESENT IN THE SAME CHROMOSOME .THEY ARE PRESENT IN THE SAME PROXIMITY . TH E ROLE OF CHROMATIN LOOPS IN TRANSCRIPTION ACT AS ENHANCER FOR THEMODIFICATION OF PROMOTER. THEY ARE SEVERAL TYPES OF LOOPING MECHANISM

1. 5-3 PRIME GENE LOOPING ,RESULTS IN TRANSCRIPTION TREMINATION AS IT BRINGS THE 5PRIME END TO 3 PRIME END

2. enhancer promoter looping it brings enahncer towards the promoter region results in transcriptional activation

3. polycomb complexes ,-epigenetic control '. transcriptional silencing

4. insulator mediator looping ; transcriptional activation from the surrounding elements .

so the answer is option E all of the above .

2.which of the following statement is false ?

myo D is a protein which helps in muscle cells diffrentiataiton .it will make the mesodermal cells to commit to a skeletal cell lineage .it plays important role in muscle cell repair .it removes cell from the cell cycle by enhancing the trancription of p21 . it plays very improtanat role in wnt signalling pathway . it is expressed in all muscle cells

option c is false .

3.which of the following couldnt be answered with RNA interference ?

option E NONE OF THE ABOVE

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