Question 13 of 27 Map A Sapling Learning macmillan learning Many enzymes have ac

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Question 13 of 27 Map A Sapling Learning macmillan learning Many enzymes have active sites that contain acidic or basic amino acids. A change in pH Can alter the charge on these amino acids as they release or accept H changing the charge and function of the enzyme The human body expends energy to maintain homeostasis, including pH homeostasis, because even a slight change in pH can have serious consequences. This is one reason why enzymes have optimum pH ranges, just as they have optimum temperatures. A deviation from the optimum pH interferes with the enzyme's activity. An example of a graph of enzyme activity (measured by reaction rate) and pH is shown. Place each of the phrases at the appropriate pH value, pH 6 or pH 8. pH 6 pH 8 the enzyme may optimum pH not bind to substrate the enzyme reaction rate 0' 1 4 6' 7' 8' 9' 10 11 2' 13 14. may be denatured is maximal pH normal ionic bonds may be disrupted Previous 3 Give Up & View solution Check Answer Next Exit Hint

Explanation / Answer

clearly, the optimal pH is at 8, since it has the greatest activity

Reaction rate then, will be maximal (at pH = 8)

the enzyme may not bind to the substrate --> in pH lower than the max value, that is, in pH = 6

the enzyme may be denaturred --> this is near the pH = 6, in which the enzyme activity is pretty low, a good explanation will be the denaturation of the enzyme

normal ionic bonds may be disrupted --> at the point in which ionic bonds remain, therefore not the performance peak, so choose pH = 6

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