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Which of the following factors contribute to the large negative G° for the hydro

ID: 51700 • Letter: W

Question

Which of the following factors contribute to the large negative G° for the hydrolysis of mixed anhydrides of phosphoric and carboxylic acids such as acetyl phosphate and 1,3-bisphosphoglycerate:

A. Destabilization of the reactant due to bond strain caused by electrostatic repulsion
B. Stabilization of the products by ionization
C. Competing resonances in the reactant relieved by resonance stabilization of the products
D. Entropy effects arising from hydrolysis and ionization

Choose the correct answer:

all of the above all except A all except B all except C all except D

Explanation / Answer

factors contribute to the large negative G° for the hydrolysis of mixed anhydrides of phosphoric and carboxylic acids such as acetyl phosphate and 1,3-bisphosphoglycerate:

A. Destabilization of the reactant due to bond strain caused by electrostatic repulsion

C. Competing resonances in the reactant relieved by resonance stabilization of the products
D. Entropy effects arising from hydrolysis and ionization

so answer is

all except B

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