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The fur of a certain animal could be white or black. The expression of the genes

ID: 520091 • Letter: T

Question

The fur of a certain animal could be white or black. The expression of the genes for black pigmentation is under the control of two transcriptional activators whose genes are on two different chromosomes. A cross of two double heterozygotes is carried out.

Part A

If both transcriptional activators are required for black fur, what would be the ratio of black to white fur among the progeny?

Enter your answer as a reduced (!!!) ratio of black:white (in that order, just the numbers, no spaces). For example: 1:0, or 1:1, 2:1, 13:5, etc.

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Part B

If either transcriptional activators is enough for black fur, what would be the ratio of black to white fur among the progeny?

Enter your answer as a reduced (!!!) ratio of black:white (in that order, just the numbers, no spaces). For example: 1:0, or 1:1, 2:1, 13:5, etc.

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Explanation / Answer

Both genes are on different chromosomes. So, they segregate independently.

If we denote transcription factors as A and B, and show dominant alleles with upper case letters and recessive alleles with lower case letters, then double heterozygote genotype is AaBb.

If both transcription factors are required to have black fur, cross between double heterozygotes result in black and white furs in 9:7 ratio.

AB

Ab

aB

ab

AB

AABB

Black

AABb

Black

AaBB

Black

AaBb

Black

Ab

AABb

Black

Aabb

White

AaBb

Black

Aabb

White

aB

AaBB

Black

AaBb

Black

aaBB

White

aaBb

White

ab

AaBb

Black

Aabb

White

aaBb

White

aabb

White

If either of the transcription factors are enough to have black fur, cross between double heterozygotes result in black and white furs in 15:1 ratio.

AB

Ab

aB

ab

AB

AABB

Black

AABb

Black

AaBB

Black

AaBb

Black

Ab

AABB

Black

AABb

Black

AaBB

Black

AaBb

Black

aB

AaBB

Black

AABb

Black

AaBB

Black

AaBb

Black

ab

AaBb

Black

AABb

Black

AaBB

Black

aabb

White

AB

Ab

aB

ab

AB

AABB

Black

AABb

Black

AaBB

Black

AaBb

Black

Ab

AABb

Black

Aabb

White

AaBb

Black

Aabb

White

aB

AaBB

Black

AaBb

Black

aaBB

White

aaBb

White

ab

AaBb

Black

Aabb

White

aaBb

White

aabb

White

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