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Map (flowchart form) the following scenarios. Include labels of the homeostatic

ID: 52193 • Letter: M

Question

Map (flowchart form) the following scenarios. Include labels of the homeostatic control pathway: Stimulus, sensor, controller, effector, response, feedback.

Due to a number of stimuli during the growth process in childhood, the hypothalamicanterior pituitary system releases growth hormone (GH; also called somatotropin) at relatively high levels compared to the post-puberty years. The stimulus for GH secretion from the anterior pituitary is growth-hormone releasing hormone (GHRH) that is produced by the hypothalamus. GH stimulates the increase in size and mass of bone tissue that accompanies overall body growth, which is also a result of GH targeting soft tissues such as muscle and connective tissues. Additionally, GH stimulates the liver to secrete insulin-like growth factors (IGFs; sometimes called somatomedins). IGFs stimulate the growth of cartilage tissues, and like GH, stimulate bone and soft tissue growth.

Explanation / Answer

Stimulus, sensor, controller, effector, response, feedback.

Due to a number of stimuli during the growth process (RESPONSE) in childhood, the hypothalamic anterior pituitary system (CONTROL CENTER) releases growth hormone (GH; also called somatotropin) at relatively high levels compared to the post-puberty years.

The stimulus for GH secretion from the anterior pituitary is growth-hormone releasing hormone (GHRH) (STIMULUS) that is produced by the hypothalamus. GH stimulates the increase in size and mass of bone tissue that accompanies overall body growth (RESPONSE), which is also a result of GH targeting soft tissues such as muscle and connective tissues (EFFECTOR). Additionally, GH stimulates the liver to secrete insulin-like growth factors (IGFs; sometimes called somatomedins) (FEEDBACK*). IGFs stimulate the growth of cartilage tissues, and like GH, stimulate bone and soft tissue growth.

* IGF-1 inhibit the release of growth hormone from the pituitary and thus, shows negative feedback regulation of growth hormone levels (negative feedback on hypothalamus and pituitary).

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