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Select the scenarios that are likely due to epigenetic modifications. A mother w

ID: 52488 • Letter: S

Question

Select the scenarios that are likely due to epigenetic modifications. A mother with a mutation in the BRCA1 gene wants her son and daughter tested. The mother inherited the mutation from her father. The son develops prostate cancer, despite inheriting the mutation from his mother, The daughter did not inherit the mutation and does not develop cancer. Female rats exposed to dioxin, a toxin, during pregnancy have offspring with a high rate of kidney disease. Females from the first generation who were not directly exposed to the toxin during pregnancy also have offspring with disease. This pattern continues for three generations. A female Siberian Husky is the only dog in its litter to be born with two differently colored eyes: blue and brown. Its mother also has one blue eye and one brown eye, whereas its father has two brown eyes. During development, undifferentiated stem cells with the potential to develop into any cell type have many regions of euchromatin, in which genes associated with pluripotency are active. The chromatin is reconfigured when cells differentiate, and these regions become heterochromatin. In mice, methylation of an allele of the agouti gene locus determines coat color. When methylated, the coat is brown, and when unmethylated, the coat is yellow. Pregnant yellow female mice are fed a diet rich in methyl groups and have offspring with brown coats. A large population of lizards inhabiting an island have red or yellow colored skin. When red lizards mate with yellow lizards, the resulting offspring are mostly red, with some yellow. A hurricane wipes out most of the population, and the next seven generations of lizards are all red.

Explanation / Answer

In the given options these two are epigenetic modifications, remaining are not.

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